Product Overview
This card covers both gonadotropin kits of the Dragon Pharma line: HCG 2500 IU and HCG 5000 IU, the same lyophilised human chorionic gonadotropin in two fill sizes. What differs is how many international units a vial holds, how much bacteriostatic water it takes and how many doses one kit provides.
Both sizes serve the same three uses: keeping testicular volume while a suppressive testosterone cycle runs, a short closing block before SERM therapy starts, and the clinical fertility setting. The format suits adult men planning cycle support or recovery.
The honest warning belongs at the top. The hormone copies the luteinising signal at the testis and leaves the pituitary untouched, so it protects testicular responsiveness but cannot switch the axis back on by itself; Nolvadex, Clomid or another SERM still closes recovery.
The Two Kit Sizes
HCG 2500 IU
The smaller fill takes 2.5 ml of bacteriostatic water at the documented ratio of 1 ml per 1000 USP units and lands at 1000 IU per ml, a figure that reads straight off a U-100 scale.
HCG 5000 IU
The larger fill takes 5 ml of the same solvent for the same 1000 IU per ml, so one vial delivers twice the doses and suits longer support. The mixed solution is good for 30 to 60 days.
| HCG 2500 IU kit | 2.5 ml of solvent, 1000 IU per ml |
| HCG 5000 IU kit | 5 ml of solvent, same 1000 IU per ml, twice the doses |
| Shared by both | Same compound, same route, same storage rules |
Mechanism of Action
Chorionic gonadotropin is a glycoprotein of 92 and 145 amino acids in its alpha and beta chains, and the beta chain occupies the luteinising hormone receptor on the Leydig cells rather than any pituitary target. That produces intratesticular testosterone without the brain's signal, which is why the testes keep size and response capacity while a cycle suppresses the axis.
Two figures shape practice: a biphasic half-life of 6 to 11 hours and 23 to 37 hours, and an intramuscular value of about 31 hours. Frequency matters more than the size of one shot, and since the testosterone made inside the testis can be aromatised, longer use at higher amounts raises estradiol.
Dosage Protocol
Amounts are counted in international units and the rows below are published practice references, not a prescription.
| Beginner | 250 IU every other day or 500 IU two to three times weekly for 4-8 weeks; limits Leydig cell desensitisation |
| Intermediate | 500 IU two to three times weekly or 500-1000 IU every other day for 2-4 weeks |
| Advanced | 1000-3000 IU one to three times weekly in short blocks; closer to clinical fertility amounts, needs estradiol control |
| Female | No bodybuilding protocol exists; clinical use in women is ovulation induction under supervision |
| Administration | Subcutaneous or intramuscular after reconstitution; serum testosterone rises within about a day |
| Kit arithmetic | At 1000 IU per ml a 2500 IU vial yields 2.5 ml and a 5000 IU vial yields 5 ml |
Sample Sequences
Three reference sequences cover support during a cycle, the end of a cycle and the fertility setting.
What to Expect
- Testicular volume. A visible increase arrives in the first one to two weeks.
- Testosterone response. Serum testosterone rises within about 24 hours, because the Leydig cells are stimulated directly.
- Estradiol. Inside the testis the new testosterone can be aromatised, so water and chest sensitivity track the amount used; Arimidex follows bloodwork, not routine.
- Desensitisation. Continuous high dosing carries this risk, which is why the schedules use short blocks.
- Limitation. It stands in for the LH signal but not for the natural pulse, so a SERM still closes the sequence.
Side Effects and Management
What appears is mostly estrogen-related and dose-dependent, showing in bloodwork before it shows in the mirror.
Storage and Reconstitution for Either Kit
Powder and mixed solution behave differently; the arithmetic is the same for both.
Which Kit Size to Choose
A closing block at 500 to 1000 IU every other day for 10 to 16 days needs roughly 4000 to 8000 IU, so one 5000 IU vial finishes it. Support at 250 IU every other day comes to about 1000 IU per week, which puts the small kit at two and a half weeks of use and the large one at five.
Storage life and spending decide the rest of it. Order the Cypionat 250 or Enantat 250 base with the Bacteriostatic water, since the vial cannot be used without the solvent.
