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S 23 Mastorin - Dragon Pharma

Dragon Pharma

S 23 Mastorin - Dragon Pharma

Oral · 10 mg/tab · 100 tabs

In stock · ships within 24h Out of stock Ships from International · U.S Domestic
CompoundS-23 (Mastorin)
ClassSARM, research
Half-lifeNot established
DetectionNot established
Liver toxicityClass risk, unquantified
Water retentionNone reported
The pack is a 10 mg tablet, 100 to a box, and the catalogue files the substance as Mastorin while the compound itself is S-23. It came out of a contraceptive development programme, which is why fertility sits in the safety picture rather than in a footnote. No elimination half-life and no urine window have been published, and the molecule is not aromatised.
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S 23 Mastorin - Dragon Pharma
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$105.00
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Quality First

All products are manufactured under strict quality standards and independently tested before release. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.

Product Overview

S 23 Mastorin by Dragon Pharma is what this card covers. The listing here is the 10 mg tablet, 100 tablets to a box, and S 23 is the compound the catalogue files under the name Mastorin. It is a research SARM that went into development as a candidate male hormonal contraceptive, and that single fact frames everything else on this page: the molecule was studied for its effect on sperm production, not for its effect on a physique. Human dosing was never published, no elimination half-life has been established, and most of the practical numbers in circulation come from non-medical use rather than from controlled work.

S-23 belongs to the selective androgen receptor modulator class, a group of non-steroidal molecules built to bind the androgen receptor with some tissue selectivity. S-23 sits at the potent end of that group: published receptor work places its binding affinity above that of older SARMs, which is exactly why it attracted attention as a contraceptive candidate rather than as a training compound. In that programme the target was dose-dependent suppression of spermatogenesis, and suppression of that kind is the opposite of what someone buying a SARM for performance usually wants.

Your order is a box of 100 oral tablets at 10 mg each, manufactured by Dragon Pharma. The catalogue name Mastorin carries no pharmacological meaning; the active substance is S 23 in both spellings, S-23 and S23. Because the compound is sold for laboratory and reference use, the pack is the unit of interest: strength per tablet, count per box, and the fact that no clinical label, no validated dosing schedule and no pharmacokinetic dataset accompanies it. Treat what you receive as a research material with a known identity and an unknown human profile.

Mechanism of Action

The mechanism is receptor binding. S-23 docks onto the androgen receptor and switches on the same gene programme that testosterone switches on, but without the conversions that make a steroid messy: it is not aromatised to estrogen and it is not reduced to DHT, so neither water retention nor gynecomastia is part of its profile. Androgen receptor activation in skeletal muscle is the reason people look at it at all, and the same activation in the testis and pituitary is the reason the contraceptive programme existed.

The suppression story is the important one. Gonadotropin signalling from the pituitary drives testicular testosterone production and sperm maturation, and a strong androgen signal tells the pituitary to cut that signalling down. In the published work this produced the intended fall in sperm output while testosterone itself was held within range, which is coherent for a contraceptive and awkward for anyone planning a training block, because the axis that supports natural production is being deliberately quieted. Nothing in the literature establishes how quickly that state reverses in humans at any given dose, so recovery timelines should be read as open questions rather than as known quantities.

Dosage Protocol

There is no studied human protocol to reproduce, so the table below is explicit about where each line comes from. The only figures with any following behind them are the lower end of the non-medical range, and even those are practice rather than data.

Studied human dose Not established: the research programme published no human dosing schedule
Non-medical range 10-25 mg a day, oral, reported practice rather than trial data
Reported cycle length 4-8 weeks in practice; no controlled comparison supports the figure
Administration One oral tablet daily, 10 mg per tablet, 100 tablets to the box
Upper limit Nothing above the reported range appears in peer-reviewed work
Female use No data; no female protocol is given here

Dividing the daily figure is a habit carried over from shorter-acting orals. Since nothing is known about how long a single S-23 dose lasts, splitting it is guesswork dressed as care.

Suggested Protocols

Because the compound suppresses the gonadotropin signal, anyone stacking it would normally be stacking it around a testosterone base rather than beside another suppressive SARM. The layouts below are drawn from the way SARMs are arranged in practice, and they are offered as structure, not as tested protocols.

Research cycle with a steroid base
S 23 Mastorin - 10-25 mg a day + Enantat 250 - 250-500 mg a week
The base supplies what the SARM suppresses; keep the block short because nothing is known about long exposure
SARM-only arrangement
S 23 Mastorin - 10-25 mg a day + MK 2866 Ostarine + GW501516 Cardarine
Two receptors addressed in one block; from a data standpoint this stacks one unknown on another
Parallel research items
S 23 Mastorin - 10-25 mg a day + MK 677 Ibutamoren - 25 mg a day + LGD 4033 - 15 mg a day
Separate substances with separate risks; no source describes this combination in humans

What to Expect

Expectation has to start with a warning about expectation. There is no body of human performance data to draw a month-by-month picture from, so the points below are drawn from what the published work does and does not describe.

No validated human dosing exists, so any schedule in circulation is borrowed from non-medical practice and is unverified.
No elimination half-life has been established; anything you read with a number attached to it is not from a pharmacokinetic study of S-23.
The compound does not aromatise, so estrogen-driven water retention and breast tissue changes are outside its expected profile.
Suppression of spermatogenesis is the documented pharmacology, which makes fertility a central consideration rather than a side note.
No official detection window has been published, and SARMs sit in the WADA S1 anabolic agent class by definition.
Liver injury is described for the SARM class as a whole in case reviews, even where S-23 itself is not specifically implicated.

Read the result the other way round as well: an unproven compound is not a weak compound, and the absence of numbers is an absence of safety information, not evidence that nothing happens.

Side Effects and Management

Class-level warnings are all that can be offered honestly. Case reviews of SARM users describe cholestatic and hepatocellular liver injury, and while S 23 is not named in every report, there is no reason to assume it is exempt from a risk that runs across the group.

Liver injury, class riskLiver panel before, during and after; stop on any jaundice or dark urine
Suppressed fertilitySemen analysis if fertility matters; avoid entirely if planning a child
Hormonal suppressionLH, FSH and testosterone at baseline and after the block
Lipid shiftsFull lipid panel, since oral androgen activity tends to move HDL down
Unknown long-term profileNo chronic human exposure data exists; shorter blocks limit the unknown

The practical precaution is dosage discipline. With no studied ceiling, the reported range is a boundary set by practice rather than by pharmacology, and going above it does not buy better data, only more exposure to a compound whose organ effects have not been characterised.

Tablets of this kind are supplied for laboratory reference, so keep them in the original blister and box and store them at room temperature, away from direct sunlight, heat and damp. A bathroom cabinet is the wrong place because of the humidity; a dry cupboard with a stable temperature is the right one. Keep the batch identification with the pack so that any later test can be tied to a specific lot, and keep the material out of the reach of children and pets.

Do not move the tablets into an unlabelled container and do not combine them with anything else in one bottle. If you are holding the compound alongside other research items, record the date the pack was opened and check the tablets for chipping or discolouration before use. Anything that has changed colour, crumbled, or smells of solvent should be set aside rather than taken.

Post-Cycle Therapy

This is the section that matters most with this compound, because sperm suppression was the whole point of the research programme it came from. Anyone using it should assume the gonadotropin axis needs support afterwards and should plan the exit before the first tablet.

Documented effectDose-dependent suppression of spermatogenesis
Reversal dataNot published for humans
Typical practiceSERP restart: Nolvadex or Clomid
MonitoringTotal and free testosterone, LH, FSH, semen analysis
Special caseAnyone planning children should not touch it

A restarted axis is usually attempted with a SERM such as Nolvadex or Clomid in the way these drugs are used after a suppressive steroid cycle, and some protocols add HCG 5000 iu while the compound clears. None of that has been validated against S-23 specifically, so the sensible position is that you are borrowing a protocol from a different drug class and should follow it with bloodwork rather than with confidence.

Every listing on this page states the exact strength, the exact tablet count and the manufacturer before you commit, so the pack you are reading about is the pack that ships. Orders are dispatched discreetly, pricing is shown in both international and US domestic terms on the product page, and the material is supplied as a research reference rather than as a medicine. If S 23 is not the right fit, the same catalogue carries the rest of the Dragon Pharma line, from injectable bases to recovery compounds, and our support team will talk through what a card actually contains before you order.

This page is educational and laboratory reference material. S 23 Mastorin is offered as research-grade material for experimental work, not as a medicine and not as a treatment for any condition. The dosage figures restate non-medical practice where no clinical data exists, and they are not a recommendation. Nothing here is medical advice. Keep the product away from children and follow the regulations that apply where you live.
What is S 23 (Mastorin)?
S-23 is a research selective androgen receptor modulator, catalogued here under the alternative name Mastorin and supplied by Dragon Pharma as 10 mg tablets, 100 per box. It was developed as a male contraceptive candidate and reached investigational new drug status before development stopped. It is unapproved, and no human dosing schedule has ever been published for it.
How does S-23 work?
It binds the androgen receptor and feeds back on the pituitary signal that tells the testes to produce sperm, which is how a contraceptive effect is achieved: sperm output falls, and in animal models it returns after the drug is withdrawn. The same feedback loop is what limits natural testosterone during use. Affinity for the receptor is high for the class, with a reported Ki of 1.7 nM.
S23 dosage - what is actually established?
Nothing in human terms. The 10 to 25 mg per day figure that appears online comes from non-medical use over four to eight weeks and is quoted here as an observation about the market, not as evidence. Since no pharmacokinetic study was ever published, even the interval between doses cannot be derived from data, and the only hard number connected to the product is the 10 mg tablet strength.
Does S-23 suppress testosterone and fertility?
Both are expected, and for this molecule they are closer to the intended mechanism than to an accident. Animal studies show sperm production falling in proportion to the amount given, with recovery after withdrawal, and any compound that interrupts the reproductive axis will pull testosterone down with it. How quickly a person recovers has not been studied, so a semen analysis is the only sensible way to know where things stand before planning a pregnancy.
S23 side effects - what can be named?
Suppression of testosterone and sperm output, a dip in libido, an HDL shift and liver risk are the items with a basis, though the liver signal is a class observation rather than a measured effect of this compound. Irritability and insomnia appear in user accounts only. There is no adverse-event table for S-23 in humans, which is the honest summary of its safety record.
Is S-23 stronger than ostarine or LGD 4033?
Labelled by receptor affinity, it binds more tightly, and the Ki figure is often quoted as proof of greater potency. Potency at the receptor and results in a human being are two different measurements, and no study has ever run S-23 against either ostarine or LGD 4033 in people. The comparison is therefore a laboratory number against a clinical one, which is not a comparison at all.
Do you need a PCT after S-23?
If testosterone is suppressed, the restart follows the convention used across this catalogue: Nolvadex at 40 mg falling to 20 mg, or Clomid at 50 mg per day. The timing cannot be calculated for this compound because no half-life has been published, so the start point has to be judged from bloodwork and from the assumption that clearance has occurred.
Is Dragon Pharma S 23 legit, or are counterfeits around?
SARM powders are widely counterfeited and brand threads about fakes exist across the market, so the question is fair for any seller. Since nobody can read a result off a hormone panel and identify the molecule behind it, the checks that matter are physical and documentary: intact seal, printed batch and expiry, consistent tablet weight, and a seller who publishes fill weight and testing data.

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