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Cagrilintide 10 mg - Dragon Pharma

Dragon Pharma

Cagrilintide 10 mg - Dragon Pharma

Injection · 10 mg · vial

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CompoundCagrilintide
ClassAmylin receptor agonist
Half-life159-195 hours
DetectionNo confirmed window
Liver toxicityLow
Water retentionNone
A long-acting amylin analogue with a half-life of 159-195 hours, which is roughly a week, so the phase 1b schedule used one subcutaneous injection weekly and peak plasma levels arrived 24-72 hours after the shot. Cagrilintide has no approved form and no ATC code, and the hepatic and fluid cells read low and none because the sources report no signal in those areas rather than because data are strong. The vial is a 10 mg lyophilisate, so every dose has to be computed from the volume of water added, and an error in that step distorts the entire schedule.
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Cagrilintide 10 mg - Dragon Pharma
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Quality First

All products are manufactured under strict quality standards and independently tested before release. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.

Buy Cagrilintide 10 mg by Dragon Pharma at Best Anabolic Steroids. The box contains 10 mg of lyophilised cagrilintide, a long-acting amylin analogue injected once a week in the research protocols and studied both on its own and alongside semaglutide. It is an unapproved research peptide with no ATC code. This page sets out what the amylin pathway does, how the weekly interval follows from a half-life of roughly seven days, the trial figures for weight change, the titration method, the partners used with it in the same catalogue, and the storage rules for a mixed vial.

Product Overview

Cagrilintide is a synthetic analogue of amylin, a hormone released alongside insulin after a meal, and it acts on amylin receptors rather than on the GLP-1 receptor. It is also written as GLXC-26801, and in combination with semaglutide the pair is studied under the name CagriSema.

What arrives is a 10 mg lyophilised vial that has to be reconstituted with bacteriostatic water. Ten milligrams is a large amount for a peptide dosed in micrograms to milligrams, so the reconstitution arithmetic decides how long the vial lasts and how wide the titration steps can be.

Two status facts belong here. No regulator has approved cagrilintide and no ATC code has been assigned to it, which is the formal way of saying it remains investigational. And it is not a hormone replacement: the amylin axis is not the HPTA, so nothing about this vial requires a recovery protocol.

Mechanism of Action

Amylin signalling slows the emptying of the stomach and produces satiety, which is a different mechanism from the incretin effect of a GLP-1 agonist. That difference is why the two classes are combined in research: one compound slows delivery of food from the stomach while the other changes the incretin response, and the axes are largely separate.

The pharmacokinetics support a weekly injection. In phase 1b work, cagrilintide showed a half-life of 159-195 hours, close to seven days, with peak concentrations 24-72 hours after the dose. Semaglutide measured 145-165 hours in the same study, which is why the two are paired on the same schedule.

A consequence of that long half-life is accumulation. A compound that clears over a week keeps building for a while when it is given every week, so a dose that felt manageable in week one is a larger effective exposure by week four. The titration rules below exist for that reason, not as a formality.

What to Expect on a Weekly Amylin Analogue

  • Days one and two. Appetite drops and a sense of fullness appear quickly, because gastric emptying slows almost immediately after the injection.
  • Weeks one and two. Nausea and smaller portions are the usual early reports from this class; the two often arrive together.
  • Weeks two to eight. Body weight falls gradually while food intake stays the same, which is the pattern described in the trial material.
  • Weeks eight to twenty. Most of the loss happens over the long stretch: in the phase 2 study, about 31.6 percent of participants lost at least 15 percent of body weight against about 4.7 percent on placebo.
  • Sufficiently full. Appetite suppression deep enough to skip meals entirely is a dose-related finding rather than a target to aim at.
  • After the last dose. Appetite returns and weight partly comes back, which is the general behaviour of this class rather than a failure of the vial.
  • The limit. The compound is not approved and the long-term safety picture is thin; the figures above come from short trials.

Amounts, Titration Steps and the 10 mg Vial

No approved dose exists. The numbers below are the amounts used in published research, not a protocol written for this vial, and the weekly interval is the one the half-life supports.

Interval One subcutaneous injection a week, as used in the phase 2 work published in 2021
Studied range 0.16-4.5 mg in phase 1b; the co-administration arm of phase 2 used 2.4 mg of cagrilintide with 2.4 mg of semaglutide
Titration Step up only after the current step is tolerated for several weeks, because exposure keeps building between doses
Female The trial data are not broken down into a separate female protocol here; the same research amounts are all that is recorded
Reconstitution Bacteriostatic water into the 10 mg cake; the concentration you create sets what each unit of a U-100 syringe delivers

Two arithmetic points are worth pinning down before the first injection. Two millilitres of water across the 10 mg cake puts the mix at 5 mg per ml, so a 500 mcg step is 10 units on the scale and a 1 mg step is 20. Half that volume of water doubles every one of the figures. Because a weekly protocol runs for months, most readers choose the weaker concentration so that small titration steps remain measurable, and use a fresh vial rather than a stronger one to avoid running out mid-block.

Combining It with Incretin Peptides in the Same Catalogue

The reason cagrilintide is bought by this audience is the CagriSema idea: an amylin analogue plus a GLP-1 agonist, each on a weekly schedule, acting on two different pathways. Every partner below is a Dragon Pharma product from the same shelf.

Dual-pathway research
Cagrilintide - weekly step + Tirze Pep 5 mg - weekly step
12 weeks and up; the amylin arm handles satiety while the incretin arm handles the metabolic side, with both doses titrated separately
Weekly schedule, single vial
A comparison shelf rather than a stack: the three compounds are studied for the same endpoint through different receptors
Non-hormonal additions
Options for readers who want to keep the protocol away from the growth hormone axis

The diluent for every one of these vials is the same bacteriostatic water, and the higher-strength Tirze Pep 10 mg vial follows the same reconstitution logic at twice the powder.

Coming Off It: Tapering Instead of PCT

Post-cycle therapy on this site exists for compounds that shut down natural testosterone production. An amylin analogue does not touch the HPTA, so a SERM block is meaningless here and the sensible exit is a step-down in dose with a break between blocks.

No PCTThe peptide does not suppress the testosterone axis, so no restart medication belongs at the end of a block
TaperingReduce the weekly step gradually rather than stopping from the top, since exposure accumulates across a long half-life; no standard schedule is documented
Between blocksA break before repeating, with appetite and weight watched during the gap
Glucose if combinedReaders combining an amylin or GLP-1 agent with insulin or a secretagogue need glucose monitoring, which is a recognised class risk
Follow-upBody weight, food intake and fasting glucose, taken before the block and repeated at the end

Nothing in the sources used for this page defines a standard taper, so the honest position is that the step-down is a precaution rather than a documented protocol.

Side Effects and the Limits of the Research

Most of the list below is a class effect of slowing gastric emptying, and most of it is dose related and manageable through titration.

Nausea and vomitingSmaller meals and slower titration; the most common reason for holding a step rather than advancing it.
Constipation or diarrhoeaFluid and fibre intake, and a review of the current step if it persists.
Appetite loss beyond intentionA dose-related effect; reduce the step and keep a nutrition record rather than accepting the extreme.
Injection site reactionCommon and local; rotate sites and follow clean technique.
Hypoglycaemia in combinationObserved when these agents meet insulin or secretagogues; glucose control is the management.
Long-term safety unprovenNo approval, no ATC code and limited long-term data, including in patients with type 2 diabetes.

Mixing the Powder and Keeping It Cold

Store the sealed vial at refrigerator temperature, between 2 and 8 degrees Celsius, in its box, and let it come to room temperature before mixing. Wipe the stopper with an alcohol swab, add the bacteriostatic water down the wall of the vial, and swirl gently until the cake is fully dissolved and the liquid is clear. Shaking a peptide is never the shortcut.

After mixing, the solution goes back into the cold at 2-8 C and is treated as usable for roughly 28 days, the working rule for a preserved multi-dose vial. Do not freeze it. Mark the mixing date on the label, draw with a fresh needle each time, and discard the vial if the solution becomes cloudy, changes colour or contains particles. Keep the vial away from sunlight and out of reach of children, and dispose of used needles in a sharps container.

Buying Cagrilintide Online

This is the amylin side of the incretin story in a single vial, and it is the right purchase for a reader who wants to work with the mechanism that the CagriSema studies are built on rather than with a GLP-1 alone. The 10 mg fill supports a long weekly titration at 500 mcg per 10 units, the page above gives the trial figures and the accumulation rule that governs how fast a step can be raised, and the storage and reconstitution rules are written out so a mixed vial is never left undated in the refrigerator. Order it here together with the incretin peptides and the bacteriostatic water from the same brand.

This material is published for educational and research reference purposes only. The compounds described are research-grade materials supplied for laboratory work and are not presented here as medicines or as a treatment for any condition. Dosing information reflects published clinical and reference data for the active substances, not a recommendation or a prescription. Nothing on this page should be read as medical advice. Keep all products out of reach of children and follow the regulations that apply in your country.
What is cagrilintide?
A long-acting analogue of amylin, a hormone released with insulin, and an agonist at amylin receptors. It is under development for obesity and type 2 diabetes and is best known as the partner of semaglutide in the combination named CagriSema. No form of it is approved, and it has no ATC code.
How does cagrilintide work?
It activates amylin receptors, which slows the rate at which the stomach empties and increases the feeling of fullness after eating. That route is distinct from GLP-1 receptor activation, which is why the two mechanisms are studied side by side instead of being treated as interchangeable. Less food is eaten because satiety arrives earlier, not because the compound burns calories.
What is CagriSema?
The name of the fixed combination of cagrilintide and semaglutide. In the phase 2 work the pairing used 2.4 mg of each, aiming at two separate satiety pathways at once. CagriSema is a development product, and the vial sold on this page is cagrilintide alone, not the combination.
Cagrilintide vs semaglutide - how do they differ?
Different receptors: cagrilintide acts on amylin receptors while semaglutide is a GLP-1 agonist. Their staying power is similar rather than identical, with 159-195 hours measured for cagrilintide against 145-165 hours for semaglutide in the same phase 1b study. Semaglutide has approved forms; cagrilintide does not.
How often do you inject cagrilintide?
Once a week by subcutaneous injection in the trial programme, matching a half-life of 159-195 hours. Peak levels arrive 24-72 hours after the shot, and because the half-life is close to the dosing interval, weekly administration builds up gradually. Site rotation and cold storage of the mixed vial are the practical points between doses.
How do you reconstitute a 10 mg cagrilintide vial?
Add bacteriostatic water down the inner wall and swirl rather than shake. With 2 ml the strength becomes 5 mg per ml, so 10 units on a U-100 syringe, which is 0.1 ml, carries 500 mcg. Store the mixed vial at 2-8 C and write the mixing date on the label, because every later dose is calculated from that same volume.
Is cagrilintide approved?
No. No regulator has approved cagrilintide, and it has no assigned ATC code, which places it in the research category. The trial data available cover phase 1b and phase 2 work, so long-term safety information is missing by definition. The vial sold here is a laboratory material rather than a finished medicine.
Is Dragon Pharma Cagrilintide legit or are there fake batches around?
Fake peptide vials are a known problem in this category, and a lyophilised cake gives nothing away by appearance. What can be checked is a legible label with the strength and batch code, an intact aluminium crimp, a cake that goes into solution completely clear, and consistency with published buyer accounts. A vial with a damaged seal or a cloudy solution should be thrown away.

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